Blar i forfatter "Mujuru, Hilda"

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    • Carotid intima media thickness in older childrenand adolescents with HIV taking antiretroviraltherapy 

      Majonga, Edith D.; Chiesa, Scott T.; McHough, Grace; Mujuru, Hilda; Nathoo, Kusum; Odland, Jon Øyvind; Kaski, Juan Pablo; Ferrand, Rashida A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04)
      Increased carotid intima-media thickness (cIMT) is reported in both adults and children with human immunodeficiency virus (HIV) in high income settings and is associated with an increased risk of cardiovascular disease, but data from sub-Saharan Africa is lacking.<p> <p>We assessed cIMT using ultrasound in perinatally HIV-infected children aged 6 to 16 years taking antiretroviral therapy (ART) ...

    • The effect of azithromycin for management of HIV-associated chronic lung disease on right heart function: Results from the BREATHE trial 

      Majonga, Edith D.; Mapurisa, Gugulethu Newton; Rehman, Andrea M.; McHugh, Grace; Bandason, Tsitsi; Mujuru, Hilda; Gonzalez-Martinez, Carmen; Odland, Jon O.; Kennedy, Neil; Ferrand, Rashida A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-20)
      Background - Right heart abnormalities and pulmonary hypertension (PH) may be secondary to chronic lung disease. Chronic lung disease is common in children with HIV. In the BREATHE trial (Trial registration: NCT02426112), azithromycin (AZM) reduced the risk of acute respiratory exacerbations in children aged 6–19 years with HIV-associated chronic lung disease (HCLD) taking antiretroviral therapy. ...

    • Effect of azithromycin on incidence of acute respiratory exacerbations in children with HIV taking antiretroviral therapy and co-morbid chronic lung disease: a secondary analysis of the BREATHE trial 

      Price, Amy; McHugh, Grace; Simms, Victoria; Semphere, Robina; Ngwira, Lucky G; Bandason, Tsitsi; Mujuru, Hilda; Odland, Jon O; Ferrand, Rashida A; Rehman, Andrea M (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-13)
      Background - In the BREATHE trial weekly azithromycin decreased the rate of acute respiratory exacerbations (AREs) compared to placebo among children and adolescents with HIV-associated chronic lung disease (CLD) taking antiretroviral therapy (ART). The aim of this analysis was to identify risk factors associated with AREs and mediators of the effect of azithromycin on AREs.<p> <p>Methods - The ...